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 Autophagy & AMPed™

Incospharm is conducting innovative research and development in age-related diseases through AMPed™ platform technology. 


What is Autophagy?

Autophagy originates from the Greek words, "auto" (self) and "phagy" (to eat). As in the etymology of the word, autophagy is known as a highly conserved mechanism to maintain cellular homeostasis by removing dysfunctional organelles and damaged proteins and converting them into energy sources for cells, thereby regulating cellular aging.
Through the research over the years, it is proved that cellular aging can be prevented and cured by stimulating cellular autophagy activity. Professor Osumi, Japan was awarded the 2016 Nobel Prize in Physiology or Medicine for his research on the role of autophagy during cellular aging. 





About AMPed™ Technology

AMPed™ (Autophagy Modulating Peptide derivatives) technology is a core platform and proprietary technology of Incospharm for designing, screening, and developing new peptide-based small molecules with autophagy activity modulating effects.